Machine-Learning-Guided Mutagenesis for Directed Evolution of Fluorescent Proteins
نویسندگان
چکیده
منابع مشابه
Two-photon directed evolution of green fluorescent proteins
Directed evolution has been used extensively to improve the properties of a variety of fluorescent proteins (FPs). Evolutionary strategies, however, have not yet been used to improve the two-photon absorption (2PA) properties of a fluorescent protein, properties that are important for two-photon imaging in living tissues, including the brain. Here we demonstrate a technique for quantitatively s...
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ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2018
ISSN: 2161-5063,2161-5063
DOI: 10.1021/acssynbio.8b00155